A comparative study of the effect of intravenous tramadol hydrochloride and intravenous clonidine hydrochloride on post spinal an aesthesia shivering

×

Error message

User warning: The following theme is missing from the file system: journalijdr. For information about how to fix this, see the documentation page. in _drupal_trigger_error_with_delayed_logging() (line 1138 of /home2/journalijdr/public_html/includes/bootstrap.inc).

International Journal of Development Research

A comparative study of the effect of intravenous tramadol hydrochloride and intravenous clonidine hydrochloride on post spinal an aesthesia shivering

Abstract: 

Background: Control of post spinal shivering is essential for optimal perioperative care, which can be achieved either by oral or parental medications. The present study is designed to evaluate the efficacy and safety of intravenous low-dose clonidine and tramadol in the treatment of post spinal shivering.
Materials and Methods: In this prospective, a double blind, randomized study, 90 ASA grade I or II, patients aged 18 – 35 years, undergoing operations under spinal anaesthesia, who subsequently developed shivering grade 3 or 4, were randomized into two groups, to receive either clonidine or tramadol. The efficacy and response rate of the study drugs were evaluated and recorded. Side effects like, nausea, vomiting, hypotension, bradycardia, dry mouth, sedation, skin rash and headache, if present, were recorded. All data were analyzed by using the Chi square test and the Z-test.
Results: There were significant differences in the response rate between the drugs (P < 0.05). Time taken from the starting of treatment to cessation of shivering was significantly less with the tramadol group (P < 0.05), however, the frequency of nausea, vomiting, sedation and headache were also significantly more in the tramadol group
Conclusion: In our study we concluded that both clonidine and tramadol control shivering. However, the response rate was higher and time taken to control shivering was lesser with tramadol, but the response rate and the side effects were lesser with clonidine.

 

Download PDF: