Correlation between hormones receptor (ER&PR) andtumor grade among sudanese female breast cancer patients

Background: A total of 88 women were selected retrospectively from this group the tissue samples of breast cancer had been analyzed using immunohistochemical techniques to understand the Hormones receptor (ER&PR)with histological grade.
Objective: To compare the expression of tumor markers (ER&PR) with tumorhistological grade.
Results: The histological grade 0 with ER +ve are (3.4%), whereas among ER – ve are (1.1%). While histological grade I with ER +ve are (2.3%), whereas among ER – ve are (2.3%). Histological grade II with ER +ve are (14.8%), whereas among ER – ve are (4.5%). Lastly, the histological grade III with ER +ve are (18.2%), whereas among ER – ve are (53.4%).Total histological grade with ER +ve are (38.6%), whereas among ER – ve are (61.4%).
The histological grade 0 with PR +ve are (4.7%), whereas among PR – ve are (1.1%). While histological grade I with PR +ve are (3.5%), whereas among PR – ve are (1.2%). Histological grade II with PR +ve are (12.8%), whereas among PR – ve are (5.8%). Lastly, the histological grade III with PR +ve are (124.4%), whereas among PR – ve are (46.5%).Total histological grade with PR +ve are (45.3%), whereas among PR – ve are (54.7%).
The correlation between ER and PR of study population among ER +ve & PR +ve are (32.6%) whereas among ER +ve & PR – ve are (5.8%). While, ER – ve & PR +ve are (12.8%), whereas among ER – ve & PR – ve are (48.8%).
Conclusion: In this study population, the expression of hormone receptors (ER, and PR)its relation with histological grade determined