Dna origami and bionanotechnology: an efficacious tool for modern therapeutics and drug delivery

DNA has long been studied because of its irrefutable significance and interaction in all the essential biomechanisms. With the help of Bionanotechnology bottom-up approach, complex 2D and 3D DNA structures can be constructed as DNA origami by using short staple strands. DNA is biocompatible to different materials or particles such as drugs, antibiotics, inorganic molecules, metal particles and small molecules that can be attached precisely at nanometer scale with the DNA origami structures to generate nanodevices and nanomedicine. DNA origami devices or structures exhibit remarkable potential regarding biomedical applications, targeted drug delivery, biosensing, diagnostics, therapeutics, nanomedicine, nanoelectronics and photonics. DNA origami is still in its initial phase and is being focused to overcome the challenges and meet up the need of timeby exploring nascent opportunities for its rapid expansion.