Effect of different hypercaloric diets on the biochemical and anthropometric parameters of wistar rats

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International Journal of Development Research

Volume: 
07
Article ID: 
10254
4 pages
Research Article

Effect of different hypercaloric diets on the biochemical and anthropometric parameters of wistar rats

Pescinini-Salzedas, Leticia Maria, Batista dos Santos, Mirele Cristina, Landgraf Guiguer, Elen, Silva Soares de Souza, Maricelma, Bueno, Patrícia Cincotto dos Santos, Santana, Mariana Leonel, Barbalho, Sandra Maria and Cressoni Araujo, Adriano

Abstract: 

Increase in the body weight, blood glucose, and abdominal fat, as well as dyslipidemias, are considered risk factors for various diseases, especially cardiovascular diseases. Thus, there is a growing search for new compounds that improve the parameters described above. In this sense, animal models that induce changes in lipid and glycemic profiles are necessary. The present study evaluated the effect of three diets on biochemical and anthropometric parameters of male Wistar rats according to G1 - treated with commercial rat food (Nuvilab®) and water ad libitum; G2 - treated with hypercaloric beverage and commercial rat food ad libitum; G3 - treated with hypercaloric rat food and water ad libitum; G4 - treated with hypercaloric rat food and drink ad libitum; G5 - treated with water and hypercaloric rat food supplemented with bacon ad libitum, and G6 - treated with hypercaloric drink and hypercaloric rat food added with bacon ad libitum. The diet in which condensed milk was mixed with water promoted an increase in glycaemia and triglycerides. In turn, the diet in which condensed milk has been integrated into the beverage and vegetable and animal fat in the diet promoted an increase in total cholesterol. No changes were observed in the weight gain and in the cholesterol fractions with the diets tested.

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