The importance of the study of plasma concentration of Selenium and oxidative stress in cardiac surgery with children cardiopulmonary bypass

Background: Several studies have evaluated the importance of the recovery of adults and children in cardiac surgery with cardiopulmonary bypass. Moreover, little is known about the plasma concentration of Selenium of the Brazilian children's population in the pre-, intra- and post-operatory with cardiopulmonary bypass. Objective: To evaluate the current Brazilian literature on cardiac surgeries in children with cardiopulmonary bypass that addresses the damage caused by oxidative stress and its relation with plasma concentration of selenium. Methods: An electronic systematic database search (MEDLINE, PUBMED, PsycINFO, and EBM Reviews) was performed to identify articles concerning the plasma concentration of Selenium and oxidative stress in cardiac surgery in children with cardiopulmonary bypass. Results: There are no scientific evidences and clinical data on the plasma concentration of Selenium and its relation with oxidative stress in cardiac surgery with children cardiopulmonary bypass in Brazil. Conclusion: Selenium supplementation and therapy after cardiac surgery, focusing on the pathophysiology of oxidative stress and the clinical usage of selenium should be performed in Brazil. There is an importance and the necessity of the study of plasma concentration of Selenium and oxidative stress in cardiac surgery with children cardiopulmonary bypass.