Salivary biomarker: A noninvasive diagnostic markers for early detection of oral cancer; a review
International Journal of Development Research
Salivary biomarker: A noninvasive diagnostic markers for early detection of oral cancer; a review
Received 20th March, 2020; Received in revised form 28th April, 2020; Accepted 29th May, 2020; Published online 25th June, 2020
Copyright © 2020, Dr. Nimmi Singh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Oral cancer is among the most common cancers worldwide. More than 90% of oral cancers are oral squamous cell carcinoma (OSCC). Diagnosis of such malignant oral tumor are often at late state with poor prognosis and the survival rate is generally very low; So considering this fact, early detection of oral cancer is urgently needed. Many recent studies have been conducted to the search for early salivary biomarkers of oral cancers. Investigation of Salivary biomarkers are simple, non-invasive and inexpensive test. Altered and abnormal DNA, RNA, and protein molecules released by malignant cells can be easily obtained from saliva. The use of saliva as a diagnostic marker may avoid unnecessary painful and expensive investigations. Salivary biomarkers could be useful tool for early detection of oral cancer.
