Screening of marine microorganisms as probiotics for production of bacteriocin

The aim of present study was to select potential probiotic from marine environment. A total of 203 strains isolated from six different coastal area of India were screened for bacteriocin production. Out of 203 strains there are 107 bacteria, 37 Yeastand 59actinomycetes. The 10 isolates from bacteria, 2 from yeast and 5 from actinomyceteshas shown antibacterial activity against human pathogens brought from MTCC culture collection. The isolates has shown maximum antibacterial activity against Klebsiella sp., Escherichia coli and  Pseudomonasaeruginosa. The optimum pH and bile salt concentration required for enhanced growth of screened isolates were found to be pH 3.0 and0.3% bile salt.