Survival rate of breast cancer patients with different age groups and the subtype of breast cancer

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International Journal of Development Research

Survival rate of breast cancer patients with different age groups and the subtype of breast cancer

Abstract: 

Purpose – The study includes the comparison between older patience having the breast cancer with the younger ones, on the basis of their survival rate and characteristics of the tumor. The tumor characteristics is a crucial to be known for the increase in survival rate of the patient. The study elaborates the tumor characteristics and helps to identify the risk factors to be considered. Methodology – Retrospective analysis of several papers were done and there analysis are being compared to provide vital information on breast cancer patient and their survival rate. Findings – Patients who are >70 years old are commonly experiencing this types of breast cancer phenotypes – HER2+, positive axillary nodes. They also have lower breast cancer specific survival. As well as their distant metastasis free survival rates are low. Younger and older patients who have ER(−)/PR(−)/HER2(−) phenotypes of breast cancer had lower survival when compared to other age groups. Research limitations/implications – The status of the phenotypes ER, PR, and HER-2 phenotypes are not based on genotype assessment which brings a biasness to the selection of patients. Also the patients might experience multiple phenotypes of cancer which might hamper the result. The breast cancer subtype is done by immunochemistry or FISH method and not on genotype evaluation which increase the bias-ness in the selection of patients. Practical implications – Development of a standard treatment for older patients is very much required. Identifying the risk factors will bring light to the discussion of a proper procedure for the treatment of patients. More clinical researches on different age group of patients contributes to the discussion. Originality/value – The paper provides an adequate information on the relation with age of the patients with their survival rate along with emphasizing the particular phenotype of cancer they had.

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