Oleoresin from copaifera martii hayne: in vitro antibacterial activity against planktonic and biofilm cells of vancomycin-resistant enterococcus faecium
Enterococcus faecium is one of the major causative agents of healthcare-associated infections worldwide. This bacterium exhibits a remarkable capacity of acquiring new determinants of resistance, including to the last resort antimicrobials. The present study reports the in vitro antibacterial effect of Copaifera martii Hayne oleoresin against vancomycin-resistant E. faecium strains and E. faecium ATCC6965, a vancomycin-susceptible strain. Oleoresin inhibited the growth of planktonic cells, displaying a minimal inhibitory concentration (MIC) of 0.060 mg/mL for most strains.