Antimicrobial activity of aqueous crude extract of sudanese solanum dubium seeds, sudanese sunnut honey and combination s. dubium seeds and sunnut honey

The purpose of the study was to investigate the in-vitro antimicrobial activity of aqueous crude extract, of Sudanese Solanum dubium seeds, Sudanese Sunnut honey, combination S. dubium seeds and Sunnut honey and combination S. dubium seeds and Sunnut honey fresh. The aqueous crude extract, of S. dubium seeds, combination S. dubium seeds and Sunnut honey, Sunnut honey and combination S. dubium seeds and Sunnut honey fresh were tested against four standard bacteria i.e.: two Gram positive (Bacillus subtilis and Staphylococcus aureus), two Gram negative (Escherichia coli and Salmonella typhi) and against two standard fungi species i.e. (Aspergillus niger and Candida albicans) using the agar plate diffusion method. The combination S. dubium seeds and Sunnut honey showed high activity (28 and 27.5 mm) against Gram negative bacteria (S. typhi and E. coli) and showed high activity (26.5 and 26 mm) against Gram positive (B. subtilis and S. aureus), also showed moderate activity (21 and 17 mm) against fungi (A. niger and C. albicans). In conclusion: Combination S. dubium seeds and Sunnut honey showed great potential activities against antibacterial as well as antifungal activity than combination S. dubium seeds and Sunnut honey fresh, S. dubium seeds and honey. The results indicate that combination S. dubium seeds and Sunnut honey extract may recommend to use as herbal drug.