Increased the risk of first trimester miscarriage with vitamin D deficiency

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International Journal of Development Research

Volume: 
08
Article ID: 
14499
8 pages
Research Article

Increased the risk of first trimester miscarriage with vitamin D deficiency

Dr. Mayyada Baqer Hasan and Dr. Sundus Muneer Hassan

Abstract: 

Vitamin D is a steroid vitamin from a group of soluble fatty hormones. A family of vitamin D compounds that include: vitamin D1, vitamin D2, and vitamin D3, can be found naturally in very few foods, as well as in the form of a dietary supplement. It is also made in the human body when the human body is exposed to ultraviolet radiation with the presence of food leads to the synthesis of vitamin D,used by the body as a supplement to improve health. Health experts advise people to be exposed to sunlight between 10 am and 2 pm or 3 pm, which is the best time to absorb vitamin D3 in the body and avoid them being exposed to the lack of vitamin D3 in their bodies. The normal range of the total 25(OH)D level is 20-100 ng/mL.[1] But Serum 25(OH)D levels do not indicate the amount of vitamin D stored in body tissues. Vitamin D is an important component of healthy body organs to function in a healthy and healthy manner. It is important for good, strong and healthy bones. It is also an important factor in the work of muscles, heart, lungs and brain well and also supports resistance to infection. Vitamin D, which gets the body from the skin after exposure to sunlight or through dietary supplements after being changed several times within the body to manage the amount of calcium in the blood and bones and intestines and to help cells all over your body to communicate properly.More study is now showing that vitamin D may be very important in treating and preventing a number of serious long term health problems. Vitamin D is different from other vitamins after entering the body turns into a hormone, This hormone is sometimes called “activated vitamin D” or “calcitriol. Vitamin D is very important to absorb minerals as calcium and phosphorus . Even if you eat foods that contain a lot of calcium and phosphorus, without enough vitamin D, you can’t absorb them into your body. The FNB established an Recommended Dietary Allowances (RDA) for vitamin D representing a daily intake that is sufficient to maintain bone health and normal calcium metabolism in healthy people. RDAs for vitamin D are listed in both International Units (IUs) and micrograms (mcg); the biological activity of 40 IU is equal to 1 mcg. Even though sunlight may be a major source of vitamin D for some, the vitamin D RDAs are set on the basis of minimal sun exposure. Analytic cross sectional study was carried out during the period from 3rd of January to 31st of Jun of 2017 (two month for each center)at three obstetric department of hospitals in Baghdad city (alkarkh , alyarmok and Almahmodea hospitals ). The hospitals where selected randomly by simple random methods. One of the hospitals was from rural area, the other from urban area and the one was teaching hospital have a cases drainage from mixed area (rural and urban). The pregnant women (or care taker) of each participants’ (mother or other member of the family)was interviewed by the researcher using a special questionnaire form constructed for this study which was revised by the supervisor. Data regarding socioeconomic status, family size were obtained from the participants, information about prior abortion, smoking, alcohol consumption, sunscreen usage, have any diseases, medications and use of food supplements. Before filling the questionnaire was informed about the nature and the aims of the study and the pregnant was included in the study according to the inclusion criteria The current study included 160 pregnant women, 80 of them with spontaneous abortions (group A) and other 80 women with normal pregnant status (group B) , in both groups the most prevalent age group was 18-30 years as (65%), while the least age group was 31- 46 years (35%) and no significant difference in age was shown between two group. The current study showed the relation between study sample and season of vit D test ,we founded that high prevalence of vitamin D deficiency was observed in women who their have more abortion but without any significant association between season and group A or group B Regarding to life style(covered and uncovered women ) and their relation with vitamin D level in this study, it was found that more than half of the participant suffered from deficiency because 62% of total sample women were covered as compared to only 38% of uncovered women with significat association (p<0.001). Also the study show the women that have more multivitamin drugs nearly equal to women that not administration to multivitamin drugs as (56%,44%) respectively and did not show any significant association between multivitamin administration and health of pregnancy. Regarding to sun exposure, our result founded more than half of women that suffered from abortion (group A) were not exposed more time to sun light as compered to healthy pregnant women(group B) as (34%,21%) respectively with significant association (p=0.01).

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