Platelet-rich plasma associated with microneedling in the treatment of skin scars: literature review
International Journal of Development Research
Platelet-rich plasma associated with microneedling in the treatment of skin scars: literature review
Received 19th January, 2020; Received in revised form 20th February, 2020; Accepted 04th March, 2020; Published online 29th April, 2020
Copyright © 2020, Kamylla Caroline Santos et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: This study aimed to provide a literature review about the association of microneedling and PRP techniques, in terms of improving the final quality of scar tissue from skin lesions. Methodology: The search and selection of articles were carried out in the national database ScieloBrasil and in the international database PubMed. Results: Microneedling aims to stimulate collagen production without causing total de-epithelialization, in a fast, minimally invasive and effective way, with promising results of the technique being observed in several studies, allowing a transdermal delivery of active agents to the skin through microchannels. Thus, the topical application of PRP helps in the improvement and acceleration of the steps for tissue repair due to its regenerative properties, being an autogenous source of growth factors. Conclusion: The association between PRP and microneedling proved to be an effective technique in the treatment of skin lesions, however, more studies are necessary in order to evaluate and adjust it for a possible implementation.