Past Issue

Alterations of the gap junctions in the process of infection with toxoplasma gondii on the intestinal epithelial cell

Toxoplasmosis is a disease caused by an obligate intracellular protozoan, Toxoplasma gondii (T. gondii). The gastrointestinal tract is therefore a major route of T. gondii infection in most cases. For this reason the intestinal epithelium is a cellular model that provides to study the first line of defense against oral infections. The gap junctions, mediated by connexin 43 (Cx43), that have the role of mediating the interactions between adjacent cells.

Diversificação e desenvolvimento rural: Agricultura familiar, erva-mate e mel

Visando identificar os resultados financeiros da cultura da erva-mate (Ilexparaguariensis) consorciada com a apicultura, em propriedade de agricultura familiar, a pesquisa apresenta possibilidades de geração de renda e diversificação de produção no âmbito das pequenas glebas rurais. A diversificação da renda é uma estratégia incentivada em propriedades praticantes da agricultura familiar pois possibilita otimizar os recursos aplicados, ter diferentes fontes de renda e propicia melhor aproveitamento da área territorial disponível.

Importância da vacinação em crianças menores de 5 anos - revisão bibliográfica

This study explores the relationship of school dropout with poverty, having as interface the family with students in the modality of Youth and Adult Education (YAE). To this end, the context and influence of the family as a generational link of poverty is a premise for the issue of school dropout, age/grade distortion, and absenteeism. Indeed, many young people and adults who are unable to complete their studies build families and throughout their lives the generational poverty system is likely to be permeated by lack of educational qualification.

Relationship between mesofauna and soil chemical parameters in a biochar-managed central amazonian yellow oxisol

The present study has aimed to assess the soil mesofauna groups' density and diversity, as well as their relationship with chemical attributes of a Yellow Oxisol being managed for fourteen years with biochar (BC) increasing doses. This study was undertaken at an Experimental Station of the National Institute for Amazonian Research, in Manaus-AM. The experimental design was in randomized blocks, with four doses of BCand four replications (blocks), totaling 16 experimental units.

Qualidade de vida e a contribuição da enfermagem no cuidado ao idoso: Revisão integrativa

O envelhecimento é uma realidade imutável e em paralelo a qualidade de vida nesta fase tem sido pauta de diversas discussões. A qualidade de vida durante este processo pode ter implicações diferentes, principalmente se tratando do fator humano, que estar a auxiliar no cuidado ao idoso. O objetivo é descrever as contribuições dos profissionais de enfermagem para a promoção da qualidade de vida aos idosos.

O impacto da atenção primaria no sus: uma revisão bibliogáfica

Objective: The following work aims to demonstrates the impact that primary health care has on the Brazilian population, in view of its programs offered, for free. Describing its evolution since before the creation of the Unified Health System until the creation of the family health strategy. Methodology: A bibliographic review was carried out. Through articles selected from the SCIELO and LILACS databases, through the descriptors: “Health Unic System (SUS)”, “Sanitary Reform”,"Health policies".

Qual é a eficácia da associação de fosfato de sitagliptina e cloridrato de metformina em comparação com o uso isolado de cloridrato metformina em adultos portadores de diabetes mellitus tipo 2 insulino-independentes?

A Diabetes Mellitus tipo 2 é o tipo mais predominante de Diabetes Mellitus e ocorre devido a resistência à insulina. A prevalência global de diabetes está em cerca de 9,3%, com mais da metade dos adultos não diagnosticados. De acordo com a 9ª edição do Atlas de Diabetes da IDF mostram que existem 463 milhões de adultos com diabetes em todo o mundo. Sobre o mecanismo da insulina, após atingir a corrente sanguínea, a insulina se liga ao receptor tirosina cinase, desencadeando duas funções, sendo a translocação da GLUT-4 para captação de glicose, e fosforilação.

Mechanisms and instruments for international cooperation of public security and defense in the fight against transnational organized crime: integrative revision

Transnational organized crime (TOC) as a phenomenon evolves every day, causing fear to the population of any country, causing irreparable damage to society, not only in terms of monetary values and perceptions of insecurity, but also in violation of the right to life. In this context, transnational criminal organizations specialize and branch out into various criminal modalities, with the possibility of interconnections, always in the illicit search for resources to obtain profits for self-financing to perpetuate power parallel to the state.

Effect of cnidoscolus urens (l.) arthur methanolic extract on virulence attributes of candida albicans sensu stricto

Candida albicans is one of the most prevalent pathogenic fungi worldwide and in recent decades has shown resistance to azoles and echinocandins. Therefore, the search for therapeutic alternatives is necessary in order to combat infections caused by this fungus. This study evaluated the chemical composition and the effects of Cnidoscolus urens methanolic extract, derived from the plant latex, on virulence attributes of C. albicans. The ability of the methanolic extract of C.