Life Sciences

Combination therapies of chemotherapeutic agents in nanoparticelsare promising strategy in releasing the drugs selectively into the targeted tissues and cells. 5-Flurouracil (5-FU) and Gemcitabine (GEM) are antimetabolites used as anticancer drugs. In this study, the antitumor activity of the combination of GEM and 5- FU encapsulated in a micro emulsion (ME) was in vitro evaluated in HCT- 116 colon cancer cells. The inhibition of cell growth was examined by the 3-(4,5­dimethyl) ethiazole (MTT) assay.

Gender mapping and analysis helps in identifying the regions and districts for priority intervention. The geography of gender has emerged as an important dimension in the gender studies. In the present study, three gender indices namely, female literacy, gender gap in literacy and sex ratio were mapped district wise for all the 30 districts in Odisha. Further, seven female literacy grades (in percentages) between 30 and 100 percent female literacy rates were identified and the gender indices were compared under each female literacy grade.

The present study on pharmacognostic activities of fruit of Wrightia tinctoria R.Br such as fluorescence analysis of powder crude drug and their chemical behavior, consistency, color and pharmacognostic analysis of fruit extracts of W. tinctoria R.Br were studied by using methanol, petroleum ether and ethyl acetate solvents. The result reveals that, the crude drug of fruit of W. tinctoria R.Br was found sticky mass in nature in petroleum ether and ethyl acetate extracts. While, semi solid mass was found in methanolic extracts.

An experiment was conducted on correlation and path coefficient analysis for fibre characters, yield and yield contributing characters in upland cotton with 11genotypes for ten characters at college farm, college of Agriculture, Rajendranagar, Hyderabad during Kharif 2007-08 to 2008-09. Correlation studies revealed significant desired association with yield for boll weight and bundle strength. Bundle strength made highly significant contribution to yield. Path matrix revealed that boll number, boll weight and 2.5% span length had maximum direct positive effect on yield.

Recent studies have shown that major grapevine viruses for the Mediterranean region are prevalent in the native cultivars that have been grown for long in Albanian vineyards. Infectious Degeneration disease complex caused by Grapevine Fan Leaf Virus (GFLV), and other viruses, comprises a common phenotype in the field, but GFLV detection in random samplings has shown low frequency.

Betel vine (Piper betle L) is  a perennial climber Betel vine (Piper betle L) is  a perennial climber cultivated for its leaf. In India, 55000 ha and in Karnataka 7143 ha area covered under this crop. This paper is the outcome of series of field visits made to the betel vine growing areas. Significant diversity observed in production aspects and also problems related to crop production. Lack of alternative standard for vine climbing, irrigation methods, fertigation, wilt, snail and un organized marketing are major problems in northern part of Karnataka.

The experiment was carried out at college farm, college of Agriculture, Rajendranagar, Hyderabad, to determine genetic variability, heritability and genetic advance estimates in upland cotton.

In Chad, the food security constitutes a problem insofar where the agricultural production cannot satisfy the demand. The main causes of this decline are often imputed to the climate whose the worsening remains certain, but also the no availability of resources genetic of the major cereals crops. Thus, some local varieties of corn are in the way of extinction because the producers cultivate the local and exotic varieties side by side, or they exchange their seeds and caused the loss of their genetic identity.

The study has attempted to analyse the suggestions expressed by the tribal farmers for better utilization of indigenous agricultural practices in Pachaimalai hills. This study was conducted in Pachaimalai hills of Trichy District of Tamilnadu. It occupies a prominent position in tribal population of Tamilnadu. A sample size of hundred respondents was selected on the basis of proportionate random sampling techniques. Data were collected by interviewing the respondents personally with the help of pre-tested and well-structured interview schedule.

The objectives of the present investigation were to find out the correlation between thyroid abnormalities and environmental pollution, occupation, industrial area, endosulphan and roof of residence used by human population. Two study groups were surveyed for the study of the prevalence of thyroid diseases. One study group is from Dakshina Kannada and the other Kasargod Districts of West coast of India. A total of 398 subjects were surveyed. Questionnaires were prepared and distributed to conduct the survey.