Past Issue

Formulation and development of famciclovir sustained release tablets using various retarding polymers

Sustained release tablets of Famciclovir were formulated by using HPMC K15M and Ethyl cellulose. The tablets were evaluated for Preformulating studies like angle of repose, bulk density, compressibility index and physical characteristics like hardness, weight variation, friability and drug content. In-vitro release of drug was performed in 0.1 N HCL and phosphate buffer pH 6.8 for twelve hours. All the physical characters of the fabricated tablet were within acceptable limits.

Formulation and evaluation of oral disintegrating tablets of flurbiprofen

The aim of this research is to formulate and evaluate Flurbiprofen Oral disintegrating Tablets. Flurbiprofen Indicated for the treatment of nonsteroidal anti-inflammatory drugs (NSAIDs). It is primarily indicated as a pre-operative anti-miotic (in an ophthalmic solution) as well as orally for arthritis or dental pain. Hence in this investigation an attempt was made to develop oral disintegrating tablets of Flurbiprofen with super disintegrating agents likeKyron T-314, Poloxomer 188 and Ac-di-Sol. Oral disintegrate tablets were prepared by direct compression method.

Preparation and evaluation of controlled release tablets containing ibuprofen

Introdução: The article discusses the general provisions of the feasibility study for the use of dual completion operation on the example of the experience of Turkmenistan, where an experimental test was conducted on four wells of the Northern Goturdepe field located in the coastal zones of the coastal waters of the Caspian Sea. Geological materials and materials of previously drilled wells were used for the design, as well as analysis of hydrodiamic and thermodynamic indicators from the existing well stock.

Gamified learning platform for health education: Usability evaluation study

The research sought to evaluate the usability of a gamified learning platform built to mediate the teaching process of students with expert judges. Methodology: this is a methodological development research, descriptive with a quantitative approach, of an applied nature. The sample consisted of 8 people with 2 evaluation segments being judges from the technology area, coming or not from the research anchor higher education institution and expert judges from the teaching area. Data collection was online by signing the TCLE. The instrument was a questionnaire adapted to Nielsen's heuristics.

Duodenal papilla neuroendocrine tumor - Case Report

Objetivo: Os tumores neuroendócrinos (TNEs) surgem das células endócrinas do trato gastrointestinal (GI); que são células enterocromafins derivadas das criptas de Lieberkühn, encontradas na mucosa e submucosa. Na papila duodenal, esses tumores são raros, portanto, sua história natural não está bem estabelecida. Dessa forma, protocolos para o manejo adequado devem ser feitos.

Popularization of science in health engendered by digital information and communication technologies

This is a study on scientific production and its insertion in society, making known the access channels and the role of the agents involved, with the objective of investigating the approximation between science and society, verifying the virtual devices available for this interaction, observing the strategies and mechanisms correspondent academics based on these results to complete the analysis. The database of the Virtual Health Library, Periodicals Capes and PubMed were the chosen research sites with the time frame from 2015 to 2021.

Distúrbios osteomusculares relacionados ao trabalho em médicos cirurgiões ortopédicos

Introdução: Os distúrbios osteomusculares relacionados ao trabalho, também definidos como lesões por esforço repetitivo, envolvem lesões que geram sintomatologia clínica relacionada principalmente ao processo álgico, fadiga, paresia, gerando declínio do desempenho profissional. Assim, esses processos lesivos são comuns em médicos cirurgiões, sendo os da área ortopédica os mais acometidos. Objetivo: O presente estudo tem o objetivo de analisar as doenças osteomusculares relacionadas ao trabalho, assim como propor medidas preventivas e de controle terapêutico.

Hyperbilirubinaemia in newborns: A Systematic review

Jaundice in newborns is characterized by the appearance of a yellowish tint to the skin and sclera of full-term as well as pre and post-term newborns and is often presente in the neonatal period affecting half to two thirds of newborns. It is characterized by elevated levels of indirect bilirubin or unconjugated bilirubin in serum concentration greater than 1.5 mg/dl. This study constitutes a bibliographic review on this condition, clinic, pathophysiology, risk factors, diagnosis and therapeutic approach.

A importância da atenção básica na prevenção secundária das doenças crônicas em idosos

Introdução: A população idosa equivale à 12% da população global, com estimativa de dobrar até 2050 e triplicar em 2100. A Organização Mundial de Saúde, conceitua o envelhecimento saudável como o “processo de desenvolvimento e manutenção da capacidade funcional que permite o bem-estar na idade avançada”, sob essa perspectiva, a crescente população idosa tem demandado cada vez mais atenção dos serviços de saúde. Objetivos: Analisar o papel da Atenção Básica na prevenção secundária das Doenças crônicas não transmissíveis em idosos.