Thyroid function in pediatric nephrotic syndrome: a hospital based observational study
Background: Nephrotic syndrome is a condition which is characterised by proteinurea, hypoprotenemia, hyperchlolesterolemia and significant edema. In children with nephrotic syndrome, it is probable to determine a hypothyroid state because of significant loss of thyroxine (T4), tri-iodothyronine (T3) and thyroid-binding globulin in presence of proteinuria.
Objectives: To determine the thyroid function test in pediatric cases of nephrotic syndrome, and to find any association and impact on thyroid harmone levels in these patients.