Serum Hepcidin quantification in differentiation of anemia
Hepcidin is a 25-amino peptide hormone that regulates iron homeostasis. Its serum quantification helps to provide the right therapeutic choice in iron-deficiency anemia and anemia in chronic diseases. We determined serum hepcidin levels using ELISA assay in 125 patients with chronic kidney diseases (CKD) [stages from II to V] (n=60), rheumatoid arthritis (n=30), β-talasemia major (n=15) and iron-deficiency anemia (IDA; n=20) for a period 2012 – 2014 year. We compare their results to control group. The reference ranges for serum hepcidin in Bulgarian population are 3.052 - 37.750 µg/L.