Formulation and evaluation of oral controlled release tablets of betahistine hydrochloride
The present study involves in the formulation and evaluation of Controlled release tablets of Betahistine HCl (16mg). The objective ofthe present study was to formulate Betahistine HCl Controlled release tablets by direct compression method by using HPMC K4M, Ethyl cellulose and Eudragit S-100.MCC was used as diluting agent, Magnesium Stearate was usedas a lubricant and Talc was used as a glident. This Controlled release the drug up to 12 hours in predeterminedrate. The formulated powder blend was evaluated for bulk density, tapped density, compressibility index and angle of repose.