Preparation of statistical copolymers of trimethylene carbonate and lactide: candidate materials for medical applications
Copolymers of trimethylene carbonate (TMC) and L-lactide (LA) with distinct compositions were prepared in solution employing [Mg(OEt)2]2∙[Ti(OBu)4] as initiator. Our results showed that the reactions in solution are considerably slower compared with the same copolymerizations carried out in bulk, however the copolymer ratios observed by NMR tracks the feed ratio excellently when the reactions were performed in toluene at 90o C.