Impact of maternal protein restriction on muscle fiber and neuromuscular junction morphology of extensor digitorum longus muscle in 21-day-old rat offspring
The fetal period is essential for the development of muscle fibers and neuromuscular junctions (NMJs). This study evaluated the effects of maternal protein restriction during pregnancy and lactation on muscle fibers and NMJs of extensor digitorum longus (EDL) muscle in 21-day-old rat offspring. Wistar rats were divided into a control group consisting of animals born to dams fed a normal protein diet (17% protein) during pregnancy and lactation, and a restricted group consisting of animals born to dams fed a low-protein diet (6% protein) during pregnancy and lactation.