Synthesis and antimicrobial activity of some new 3-amino-6-(2'-aminophenyl)-1,2,4-triazin-5(4h) one
3-(Acyl/aroyl/ alkyl) amino-6- (2'-Acyl/aroyl/ alkyl) amino phenyl) - 1,2,4-triazin-5(4H) ones (3-10) have been synthesized derived from 3-amino-6-(2'-amino phenyl)- 1,2,4-triazin-5(4H) one (2). Structure of the new products have been established upon their elemental and spectral date. The newly prepared compounds showed good anti-microbial activity for more pathogenic microorganisms, prevalence of Staph. aureus growth and non-growth, that the growth had decreased almost at 9h and had increased number of non-growth bacteria by compound number 10. E. coli were inclined but less than Staph.