Immunotherapy in the treatment of Laringeal recurrent respiratory Papillomatosis (clinical Study)
Introduction: Recurrent respiratory papillomatosis (RRP) is a relatively rare disease. Although histologically RRP is a benign entity, it is a major clinical problem because of its location, often dramatic presentation due to significant airway obstruction, the ongoing resistance to therapies, frequent recurrences, spread to the lower respiratory tract and esophagus (aggressive forms) and the possibility of malignant transformation into squamous cell carcinoma.