Past Issue

Escherichia Coli Meningitis in an Immunocompromised Oncology Patient - Case Report

This is a case report that highlights the diagnostic and treatment complexities of an oncology patient (rectal neoplasia) with Escherichia coli meningitis. The study focuses on laboratory findings and imaging results leading to the definitive diagnosis, addressing signs and symptoms, blood culture history, treatment administered, and clinical outcome.

Clinical Evaluation of Nityavirechana and Trayodashangaguggulu for Managing Katigraha (Low Back Pain) in Overweight and Obese Individuals: An Open-Label Single-Arm Study

Introduction: Low back pain (LBP) refers to discomfort in the lower back. It is a common issue affecting all age groups. There is a correlation between LBP and Katigraha in Ayurvedic texts. According to modern science, LBP is characterized by persistent pain in the lower back. Ayurveda views LBP as a manifestation of doshic imbalance involving Vata, Pitta, and Kapha. Aim of the study: Management of Katigraha with Nityavirechanausing Gandharvahastaditaila, Nirgundikwatha, and Trayodashanagaguggulu.

Effectiveness of Makerere University E-learning Environment (Muele) in the Lens of Delone and Mclean’s (2003) Information Systems Success Model: a Qualitative Study

The global trend of embracing electronic learning (e-learning) in higher education raises a crucial need to have evidence of achieving the investment goals. In other words, policy makers and managers are faced with a question as to whether their decisions to invest in ICT in teaching and learning have yielded the intended goals or not. Hence, the aim of this study was to explore how different stakeholders in Makerere University perceived effectiveness of Makerere University E-Learning Environment (MUELE).

Physicochemical Evaluation of Irrigation Water and Determination of Heavy Metals in Baixa de Hulene-b, Maputo: Impacts on Public Health

To assess the effects of heavy metals (lead, mercury, and silver) present in the irrigation water from Baixa de Hulene-B, this study examined both physicochemical and additional chemical parameters in the water. The water floods the aquifers and vegetable cultivation areas during rainfall, carrying waste and solid refuse from the region's cities. This contamination affects the quality of the water used for irrigation, leading to health problems. The research was descriptive and explanatory in nature and employed a quantitative approach using deductive and comparative methods.

Benzodiazepines: are Clonazepam Better than Lorazepam and Alprazolam, a Comparative Review Article

Anxiety is a common occurrence in humans, and it appears in a variety of anxiety disorders, making it an essential clinical focus. Recent advances in nosology, epidemiology, and psychobiology have resulted in a better understanding of anxiety disorders. Advances in medicine and psychotherapy for these diseases have given patients reasonable hope for symptom alleviation and functional improvement.

Functional Capacity of Community Animation Cells (CAC) and its contribution in improving nutritional status for children under five in Bunyakiri Health Zone in South Kivu, Democratic Republic of Congo

Indroduction: Malnutrition significantly contributes to high mortality rates among children under 5 in sub-Saharan Africa, with the eastern Democratic Republic of Congo (DRC) being particularly affected. In response, various strategies, including community outreach units, have been implemented to enhance child nutrition, specifically in the Bunakiri health zone of DRC's Southern Province. This study seeks to evaluate the functional capacity and the contribution of these CACs on improving the nutritional status of young children in the area.

Use of Cannabinoids in Alzheimer's Disease: integrative Synthesis of the Literature

Introduction: Alzheimer's disease (AD) is an incurable neurodegenerative condition with limited therapeutic options. Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC), derived from Cannabis sativa, show therapeutic potential due to their neuroprotective properties and interaction with the endocannabinoid system (ECS). Objectives: Synthesize and evaluate the available scientific evidence on the use of cannabinoids in the treatment of AD.

Prediction of Physicochemical, Pharmacokinetic and Toxicological Parameters of Antimicrobials in Phase III Clinical Studies

In silico analysis importance was recognized. It provides a predictive evaluation of the molecular behavior, revealing physicochemical properties and pharmacokinetic and toxicological informations that determine how much promising is a molecule to advance to other pharmaceutical tests. Therefore, this work aimed to present the traditional antimicrobials in phase III clinical studies, attaching, through in silico analysis, their pharmacokinetics, adverse effects and toxicity to their molecular structure and physicochemical properties.

Prevalence of Patellofemoral Pain Syndrome in Patients with Anterior Knee Pain in South Gujarat

Introduction: Abstract- Patellofemoral pain (PFP) is recognized as one of the most common lower-extremity disorders encountered by orthopedic physical therapists. PFPS is defined as pain around (peripatellar) or behind the kneecap (retro patellar) that is aggravated by activities loading the knee joint, such as running, squatting, climbing stairs or even prolonged sitting with knee flexion above 90 degree. It is one of the most common knee conditions clinicians encounter in young and active individuals.

How to Train Teachers Prepared to use Digital Technologies that Influence the Social Movements of Children at School: A Systematic Review

Introduction: Teacher training is a central element in the development of quality education. This training involves not only the acquisition of pedagogical knowledge, but also the development of skills that allow educators to adapt to new demands and challenges. The general objective of the study was to critically analyze teacher training for the use of digital technologies that influence children's social movements at school.