The protective effect of different doses of alpha lipoic acid against hepatotoxicity of sodium nitrite in rat
Sodium nitrite (NaNO2) presents in vegetables and is routinely used as a color fixative and as a preservative for meat and fish. Chronic ingestion of NaNO2 induced abnormalities in the biochemical parameters associated with the oxidative stress. The present study was carried out to investigate the protective efficacy of alpha lipoic acid (ALA) on the liver and kidney function tests and the oxidative stress alteration induced by NaNO2 in male albino rats; moreover the microscopical examination was studied.