Secondary haemophagocytic lymphohistiocytosis in an immuno-competent patient of extrapulmonary tuberculosis
Haemophagocytic lymphohistiocytosis (HLH) results when critical regulation of natural termination of immune/inflammatory responses is disrupted or overwhelmed. The predominant clinical findings of HLH are fevers (often hectic and persistent), pancytopenias, hepatitis and hepatomegaly and splenomegaly. The diagnosis is established by fulfilling one of the HLH 2004 criteria. A 55 years male patient presented with fever, abdominal pain and abdominal distension. Examination revealed cervical lymphadenopathy. and hepato-splenomegaly.