Health Sciences

Prediction of Physicochemical, Pharmacokinetic and Toxicological Parameters of Antimicrobials in Phase III Clinical Studies

In silico analysis importance was recognized. It provides a predictive evaluation of the molecular behavior, revealing physicochemical properties and pharmacokinetic and toxicological informations that determine how much promising is a molecule to advance to other pharmaceutical tests. Therefore, this work aimed to present the traditional antimicrobials in phase III clinical studies, attaching, through in silico analysis, their pharmacokinetics, adverse effects and toxicity to their molecular structure and physicochemical properties.

Prevalence of Patellofemoral Pain Syndrome in Patients with Anterior Knee Pain in South Gujarat

Introduction: Abstract- Patellofemoral pain (PFP) is recognized as one of the most common lower-extremity disorders encountered by orthopedic physical therapists. PFPS is defined as pain around (peripatellar) or behind the kneecap (retro patellar) that is aggravated by activities loading the knee joint, such as running, squatting, climbing stairs or even prolonged sitting with knee flexion above 90 degree. It is one of the most common knee conditions clinicians encounter in young and active individuals.

How to Train Teachers Prepared to use Digital Technologies that Influence the Social Movements of Children at School: A Systematic Review

Introduction: Teacher training is a central element in the development of quality education. This training involves not only the acquisition of pedagogical knowledge, but also the development of skills that allow educators to adapt to new demands and challenges. The general objective of the study was to critically analyze teacher training for the use of digital technologies that influence children's social movements at school.

Assessment of medication discontinuation in hypertensive and diabetic patients after bariatric and metabolic surgery

Introduction: Epidemiological studies show a significant acceleration in the prevalence of obesity in Brazil and worldwide, making it a public health issue, primarily due to the increased risk of diseases such as systemic arterial hypertension (SAH) and type 2 diabetes mellitus (T2DM). The first-line treatment for obesity is lifestyle modifications and pharmacological measures.

Comparative study of evaluation of sensory processing disorder with the Atlas.Ti

Sensory Processing Disorder (SPD) is reflected in unexpected actions and inappropriate behavior for no apparent reason. It is a complex condition that involves the central nervous system and is not evident in clinical examinations. Introduction: Identifying the patient's reactions to everyday situations helps health professionals to recognize sensory integration difficulties and establish a treatment plan, which begins with assessment. Objective: To identify the assessment most commonly adopted by SPT researchers.

A Study to Assess the effect of Structured Teaching Programme on Knowledge Regarding Prevention of Bullying Behaviour Among Students of Selected Nursing College, Bengaluru

Introduction: Bullying has become a major issue in the social environment causing an impact on physical health, mental health and social life of an individual. It is pernicious in its impact even if it is often less visible and less readily identifiable than other public health concerns. It is very important to have updated Knowledge regarding the prevention of bullying behaviour among adolescents.

Intensive care units admissions for hypertensive disorders in pregnancy and the puerperium: an epidemiological analysis in pernambuco for a period of one decade

Introduction: Hypertensive disease of pregnancy represents the most common complication during pregnancy, presenting significant risks to maternal and fetal health. This condition is characterized by clinical and laboratory impairment, with elevated blood pressure levels that can range from mild to severe. Objective: To analyze the prevalence of epidemiological aspects and the main causes of ICU admission due to the treatment of proteinuria and hypertensive disorders during pregnancy and the postpartum period in Pernambuco.

Preparation and Characterization of Celecoxib Matrix Transdermal Patches

Transdermal Drug Delivery systems represent a category of topical, self-contained discrete dosage forms designed to deliver drugs at a controlled rate to the systemic circulation when applied to intact skin. This research reports the successful preparation of a Celecoxib transdermal patch using the solvent casting technique. Various plasticizers, including PEG, glycerol, and oleic acid, were employed in combination with different solvent ratios. The formulation incorporated polymers such as methylcellulose, guar gum, HPMC, and ERS 100.

Linking Post-Treatment Rehabilitation with Healthcare Roles: How Nurses and Technicians Influence Patient Satisfaction

Post-treatment rehabilitation is a critical component of healthcare that significantly influences patient recovery and long-term outcomes. This review explores the interconnected roles of nurses and technicians in delivering effective post-treatment rehabilitation and its impact on patient satisfaction. Nurses play a vital role in patient education, monitoring, and emotional support, while technicians ensure the proper functioning of medical equipment and therapies. Through a collaborative care model, both healthcare roles contribute to improving service delivery and patient experiences.