The Immune Defense against Mouse Para Coccidioidomycosis Offered by peptide p10 is significantly Enhanced by poly (Lactic Acid-Glycolic Acid) Nanoparticles
Background and goal: This study describes the development and testing of a sustained delivery method for the immunomodulatory peptide P10 with the goal of lowering the peptide's in vivo degradation and the quantity needed to trigger an immunological response that protects against Para coccidioidomycosis. Methods of the experiment: To simulate the chronic form of Para coccidioidomycosis, BALB/c mice were infected with the yeast Paracoccidioides Brasiliense’s.