Rbm3 and cirp may play an important role as avasodilator. a preliminary study
It is now well accepted that e-NOs is one of target genes of HIF-1 and it plays an important role as a vasodilator or angiogenesis. We found in our series of immune his to chemical study that anti- RBM3 and CIRP antibodies were able to stain the nucleuses of neurons, myocardial cells and cells in the blood vessels existing in the newly infarction area of the brain and myocardium, although moderate or feeble reactivity with those antibodies were observed in sub-acute and/or chronic infarction area.