Salivary biomarker: A noninvasive diagnostic markers for early detection of oral cancer; a review
Oral cancer is among the most common cancers worldwide. More than 90% of oral cancers are oral squamous cell carcinoma (OSCC). Diagnosis of such malignant oral tumor are often at late state with poor prognosis and the survival rate is generally very low; So considering this fact, early detection of oral cancer is urgently needed. Many recent studies have been conducted to the search for early salivary biomarkers of oral cancers. Investigation of Salivary biomarkers are simple, non-invasive and inexpensive test.