Tumor dormancy in population of cancer stem cells: gene interactions by bioinformatics
Introduction: Cancer stem cells (CSC) correspond to a small population of cells tumor with the ability to remain hidden. This contributes strongly to the resistance to antitumor therapies, the occurrence of relapse and metastasis. Objective: Inter relate the gene interactions networks of tumor dormancy (TD) and CSC. Methods: Genetic interaction networks of CSC and DT were identified in the Gene Cards® database. The maps of genomic interactions were performed using the software STRING 10.0.