Past Issue

Tumor dormancy in population of cancer stem cells: gene interactions by bioinformatics

Introduction: Cancer stem cells (CSC) correspond to a small population of cells tumor with the ability to remain hidden. This contributes strongly to the resistance to antitumor therapies, the occurrence of relapse and metastasis. Objective: Inter relate the gene interactions networks of tumor dormancy (TD) and CSC. Methods: Genetic interaction networks of CSC and DT were identified in the Gene Cards® database. The maps of genomic interactions were performed using the software STRING 10.0.

Metrics for analysis of technological maturity of academic spin-offs through technology readiness levels

This work aimed to develop a framework for assessing the technological maturity of companies that are born from research groups of educational institutions or research centers. These companies, commonly called academic spin-offs, usually start their activities after participating in incubation processes performed by academic incubators, where they learn to direct their efforts to business maturity, disregarding the technological maturity required for the development of their final product.

Profile of patients using hydroquinone in treatment of melasma

This article presents the interest in studying about the use of hydroquinone for the treatment of melasma by patients with hyperpigmentation as a cutaneous alteration, characterizing the profile of these patients, and to verify their knowledge about the risks caused by indiscriminate use. This drug also describes the main risks of using hydroquinone without medical and pharmaceutical guidance, pointing out the importance of the pharmaceutical professional during the dispensing of hydroquinone.

Cuidados de enfermagem relacionados à redução de incidência de lesão por pressão em unidade de terapia intensiva

Os eventos adversos na Unidade de Terapia Intensiva (UTI) são extremamente preocupantes, por conta do perfil de gravidade clínica de seus pacientes. Dentre os eventos mais comuns, os casos de Lesão por Pressão (LP) têm uma maior prevalência dentro desse ambiente. Normalmente, estas se encontram sobre proeminências ósseas, resultando da pressão ou de uma combinação entre pressão e forças de torção.

Entrepreneurship in the pharmaceutical sector: a study about the entrepreneur profile among university students in a private hei

This paper aims to characterize the entrepreneurial profile of students from the first to the tenth semester of the pharmacy course of a private HEI, in Vitória da Conquista. To this end, it sought to identify if the student has entrepreneurial behavioral characteristics (CCE's) that favor the entrepreneurial profile. The results show that students have the ten CCE's, and the opportunity-seeking feature obtained the highest score among students, but the other characteristics need to be improved during the pharmacy course.

The role of nursing in mental health in the primary care

Objective: To analyze scientific evidence found in literature about the role of nursing in Mental Health in the Primary Care. Methods: This article is an integrative literature review. To survey articles in the literature, the databases LILACS, SCIELO and BDENF were used. Were found 53 studies, of which 10 met the inclusion criteria. Results: From the analysis of scientific productions, it was possible to verify that most nurses feel unprepared to work in the area of mental health in primary care, or even those who said they feel prepared, few were able to detail this knowledge.

Challenges of the care network on reference and counter-reference: an integrative review

Objectives: To identify in scientific productions, which are the main challenges that network professionals face regarding the referral and counter-referral process. Methodology: This study is an integrative literature review, conducted in the first half of 2018, at the Virtual Health Library (VHL), based on the Latin American and Caribbean Health Sciences Literature, Data Base on the Nursing (BDENF), and MEDLINE (Online Medical Literature Analysis and Retrieval System). After considering inclusion and exclusion, they were used and analyzed through a synoptic table.

Mothers of children with autism spectrum disorder show more demonstrative and directive and less imitative and playful behavior with their children

In this study, videotapes of play interactions were coded for the behaviors of 4- to 6-year-old nonverbal children with autism spectrum disorder (ASD)(i.e., looking at the adult, initiating, imitating, and being playful) and their mothers’ and an imitative examiner’s behaviors (i.e. demonstrating, directing, imitating and being playful).ANOVAs revealed that the mothers spent more time demonstrating and directing versus the experimenter who spent more time being playful and imitating the child. The children spent more time looking at their mothers and more time imitating the experimenter.

Manual lymphatic drainage in treatment of geloid edema fiber: a case study in two women

The current enhancement of appearance, increasingly widespread in the media, has led people to seek to achieve an imposed standard by undergoing a series of procedures to achieve the ideal appearance. Among the recurring and most prevalent discomforts in women, is the fibroid geloid edema- FEG, which is one of the reasons for greater demand for clinical treatment. This study aims to describe the action of manual lmphatic drainage in the treatment of fibroid edema in women in the thigh region.

Orientação médico-obstétrica no pré natal: influência na escolha do tipo de parto e amamentação

Esta é uma pesquisa de abordagem qualitativa, do tipo descritiva, que visa avaliar a influência das orientações fornecidas às gestantes durante as consultas de pré-natal nas Unidades de Saúde da Família do Município de Vitória da Conquista – BA, na escolha do tipo de parto e amamentação. A coleta de dados se deu através de entrevistas com gestantes de três Unidades de Saúde da Família, realizadas na sala de espera nos dias da consulta de pré-natal.