Life Sciences

Prevalence of flu-like syndrome among chronic hepatitis c infected patients treated with the first line combination therapy (pegylated interferon α-2a and ribavirin)

Flu-like symptoms usually occur during the first weeks of treatment with administration of pegylated interferon α-2a and severity declines thereafter. These symptoms include fever, chills, headache, arthralgia, and myalgia.

Comparative study of gene expression data set using biclustering methods

Expression technology, such as high density DNA microarray, allows us to monitor gene expression patterns at the genomic level. Advent of this technology leads to the new challenges of extracting biologically relevant knowledge from such large gene expression data sets. As a result, data mining of gene expression data has become an important area of research for biologists. Suitable mining techniques will contribute to get into the insight of the gene-gene relationships and that may further lead to discover hidden facts related to any species or microbes.

Prenatal exposure to valproic acid and gabapentin on maternal, fetal, neonatal weight gain and postnatal development

Weight gain in adult patients with hyperphagia is the main concern of long term antiepileptic therapy, but little concern has been taken in pregnant women and their fetal development (weight) as well as long- lasting impact on postnatal growth of the offspring.Sperm positive female C.F. rats were exposed to different doses of Valproic acid (VPA) (50,100 and 200mg/kg body weight) and Gabapentin (GBP) (300 and 400 mg/kg) from gestation day (GD) 0-20 orally with control subjects.Maternal food intake and body weight gain were recorded daily.

Effect of inclusion of research projects on academic outcome of medical undergraduate students

The number of undergraduates involved in research activities is very less in Indian medical Colleges. Usually they are focused towards their academic performance and find research activities as time consuming and totally extracurricular. In this study we tried to observe any positive or negative effect of doing short term research on academic performance and at the sametime we tried to obtain students' personal views on doing research AIM: We focused on analyzing the effect of research on academic performance of undergraduate Medical students.

The effect of various pollutants on fishes and amphidia fauna of Damoh dIstrict

All the 8 lakes and 3 rivers in Damoh District, were studied to analyse the effect of change in Physico-chemical parameters on the planktons, fish and anphibian population and distribution. Due to manhandling of these water bodies, the parameters changed, which led to population fluctuation of phytoplanktons and fish and anphibian.

Comparative effects of organic manure (tithonia diversifolia and bat-guano) on the crop yield of corn (in monoculture and in association with cowpea) in ngandajika region in central democratic republic of Congo

Globally, agriculture is still facing the challenge of supplying humanity with food, every year millions of people are added to the billions to be fed. Food production faces increasing population, a deficit to cover the needs of the global population with food (Francis, 1986). The famine in some vast regions of the world and continues to make havoc in Sub-Saharan Africa and the DRC in particular, the scourge is increasingly felt. The spaces to produce the food are reduced with the erosive phenomenon and flooding caused by global warming.

In-vitro studies on effect of methanol and water extracts of detarium microcarpum guill and perr stem bark on root-knot nematode (Meloigogyne Javanica)

Methanol and water soluble extract of Detarium microcarpum Guill and Perr effect of Roo-knot nematode (Meloidogyne javanica) were studied in Laboratory of the Department of Crop Protection, Modibbo Adama University of Technology, Yola in 2014. Root-knot nematode (M. javanica) juvenile mortality in the Laboratory and chemical compound responsible were ascertained.

Interplay between calorie restriction, antioxidant and mitochondrial metabolism

Mitochondrial dysfunction is heavily noticed by increasing production of reactive oxygen species (ROS) production that are generated as a byproduct of aerobic respiration and various other metabolic processes. To regulate the level of ROS in the human body calorie restriction (CR) and antioxidant plays a dramatic role in maintaining the metabolism of the body. CR is a non – genetic intervention defined as a reduction in calories intake without malnutrition. CR simply slows down the metabolism of the body as a result less production of ROS occurs and hence prevents from cellular damage.

Factors influencing adoption of conservation agriculture by smallholder farmers of domboshawa, mashonaland central, Zimbabwe

Agricultural productivity in sub Saharan African (SSA) countries, especially Zimbabwe, has been reducing despite the many investments made in the development and promotion of agricultural technology. Conservation agriculture (CA) is a technology that has availed solutions to agricultural production constraints, land degradation and low crop yields in Zimbabwe. Technology adoption is one key aspect that enhances productivity in any farming system; however, adoption is influenced by several factors. This study sought to determine the factors affecting CA adoption in Domboshawa, Zimbabwe.

Antioxidant activities and effect of ph and temperature on the antibacterial efficacy of stem bark extracts of trichilia heudelotii planc (harm)

This study evaluated the antioxidant and effect of pH and temperature on the antibacterial efficacy of the stem bark extracts (acetone and ethanol) of Trichilia heudelotii on some pathogenic bacteria using standard procedures. The percentage yields were 9.62±0.01% and 10.20±0.10% while the antioxidant activity of the plant extracts was concentration dependent with IC50 of 1.31±0.15 and 1.55±0.03 for ethanol and acetone extracts as compared to reference ascorbic acid (0.40±0.15).