Health Sciences

Management of a rare chronic blistering autoimmune skin disease: Pemphigus Vulgaris

Pemphigus vulgaris is an autoimmune, intraepithelial, blistering disease affecting the skin and mucous membrane. The immune system produces anti bodies against specific proteins in the skin and mucous membrane. These anti bodies break the bonds between skin cells. This leads to the formation of a blister. The exact cause is unknown. It is mediated by circulating auto antibodies directed against keratinocyte cell surface. The disease arises most often in middle aged or older people, usually starting with a blister that ruptures easily. The lesions can become quite extensive.

Determination of antioxidant potential from two filamentous fungi isolated from the dried fig

The antioxidant capacity and antioxidant constituents of two filamentous fungi (Acremonium charticola and Rhizopus oryzae) isolated from the dried Fig were evaluated in the present study. The antioxidant capacity of the fungal crude extracts was assessed based on the 2,2 azino-bis(3-ethyl-benzthiazolin-6-sulfonicacid) (ABTS) method. Total phenolics were determined based on the Folin-Ciocalteu method, while the flavonoids content in the fungal extracts was determined by the spectrophotometric method with aluminum chloride.  Total tannins were estimated by the Folin-Denis method.

The dependence of proton related acidity inside erythrocytes from the proton conductance in the previous 8 stages of the full 9 stepped cycle of proton conductance

It is established that in case of changing of electrons and protons normal conductance by uncoupler as rotenone - inhibitor of mitochondrial respiratory chain complex I, inhibitor of mitochondrial hydrogen atom transport at NADH: ubiquinone oxidoreductase level, the significance of the pH value in the outside of isolated erythrocytes, the significance of the pH value after the partial hemolysis of isolated erythrocytes, the significance of the pH value after the full hemolysis of isolated erythrocytes changed to alkaline side.

Disturbance fields in maxillo-facial area as a reason for idiopathic urticaria and angioedema

In search of other causes of idiopathic angioedema and urticaria we investigated the possible consequences of the disturbance fields in MFA in two patient groups: group 1 - patients with angioedema (n = 11) and group 2 - patients with urticaria and angioedema (n = 39), in total 50 people. We found that compared with the control group (n = 60 healthy patients) there is a statistically significant difference between higher values of DMFT index and presence of active foci in MFA. Angioedema is more typical for patients of a higher mean age (56,5 ± 10,59).

Effect of caffeine on exercise performance among untrained medical students

The purpose of the study was to examine the effect of moderate dose (5mg /kg) of caffeine ingestion on pulse rate, blood pressure and energy expenditure during a steady state e xercise period with a standardized power output as well as during a set time period.  In this study participants were required to cycle with maximum effort.  Eighteen  healthy, overweight, sedentary, male, first year  MBBS students of  JNMC,  completed 15 minutes of steady state of cycling  exercise  at a standardized  power output equating to 65% of HRmax.

Nasya – how it works: An ayurvedic concept

In Samhitas Nasyakarma has been described in detail. Charaka in Sutrasthana first chapter has given the synonyms of Nasyakarma, in Siddhisthana has classified Nasyakarma depending on the medicines used and on the pharamacological action and also has stated indications and contraindications for Nasyakarma. He has explained the procedure along with complications and samyak and asamyak yoga features. In Vimanasthana he mentions different types of Nasyakarma depending on the parts of a plant used. Sushruta has defined Nasyakarma as instillation of medicine through Nose in Chikitsasthana.

Effect of reflex rolling on oxygen saturation and incubation period in preterm neonates with respiratory distress syndrome

Objective: The present study aimed at investigating the effectiveness of reflex rolling on incubation period and oxygen saturation in preterm neonates with respiratory distress syndrome.
Background: Respiratory distress syndrome in premature neonates is one of the leading causes of neonatal morbidity and mortality in developing countries. Reflex rolling is tactile stimulation technique used to improve respiration.