Utility of estrogen receptor alpha (ERα), progesterone receptor (PR), and her2 expression in primary breast carcinoma in Iraqi Women
Background: Immunohistochemical markers can be used to classify breast cancer into distinct biological subtypes that behave differently. The Hormone receptors (estrogen receptor (ER) and progesterone receptor (PR)), and human epidermal growth factor receptor-2 (HER2) profile of breast carcinoma have a significant role in determining patient's prognosis, in addition to early detection of cancer, planning treatment and monitoring response to treatment. Increase use of tumor markers represents a shift in understanding of the basic biology of breast cancer, and treatment modules.